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Analytical serviceStability & Degradation
Stability investigation follows the chemical integrity of a material through time and conditions: the appearance of degradation products, oxidation, hydrolysis, aggregation and the analytical changes that accompany them. Stability conclusions apply to the investigated methods, conditions and time periods — they are not general statements about the molecule.
Illustrative figure — the shape of the measurement, not a result.
Time-dependent integrity data, degradation profiles and stability-indicating measurements.
Methodology classes
- Stability-indicating chromatographic methods
- Degradation investigations under specified stress
- Environmental stress studies (temperature, light, humidity, pH)
- Moisture determination and physicochemical measurement
Applicable sample categories
- Peptides in solid or solution form
- Formulated preparations
- Packaged materials under storage conditions
- Comparative formulations
Measurable parameters
- Time-dependent integrity of the principal component
- Degradation-product formation and distribution
- Oxidation, hydrolysis and aggregation markers
- Physicochemical changes under the stated conditions
Reporting outputs
- Time-point tables and degradation profiles
- Stability-indicating measurements with method reference
- Conditions, time periods and storage stated explicitly
- Observations limited to the investigated scope
Fees for this service
Fees are per sample in pounds sterling, excluding VAT, and apply to the methods and scope described on the corresponding service page. Where no fee is listed, the investigation is scoped and quoted after a pre-submission enquiry. Multi-sample series and recurring programmes are priced on request.
| Stability & degradation | Fee |
|---|---|
| Reconstitution stability — purity and content at day 14 and day 28, 2–8 °C | £296 three time points |
| Additional reconstitution time point | £221 per time point |
| Stability study — per condition, per time pointdesign, conditions and time periods agreed at enquiry | Request a quotation |
| Forced-degradation study — stress conditions, degradation profile, stability-indicating method | £11,460 from, per study |
Describe the sample and the question.
A pre-submission enquiry establishes analytical suitability, experimental requirements, sample handling and reporting expectations before any material is sent.